table

EL Husseiny's USMLE Step 1 Preparation Program Schedule

Subjects	Sub-subjects	Content	Number of Sessions	Duration
Microbiology & Antimicrobials			18	40 Hours
	Microbiology 1	Normal Flora Bacterial structure Microbial Pathogenicity Gram Stain Oxygen requirements Intracellular bugs Encapsulated bacteria Encapsulated bacteria vaccines		(2 Hours & 46 minutes)
	Microbiology 2	Bacterial Toxins Bacterial growth Bacterial genetics Bacterial viruses (Bacteriophages)		(2 Hours & 14 minutes)
	Microbiology 3	Staphylococcus aureus Staph epidermidis Staphylococcus saprophyticus Streptococcus pyogenes Streptococcus agalactiae Viridians Streptococci Streptococcus pneumoniae		(3 Hours & 16 minutes)
	Microbiology 4	Enterococcus faecalis/faecium Bacillus anthrax Bacillus cereus Clostridium tetani Clostridium botulinum Clostridium perfringens Clostridium difficile Listeria monocytogenes		(3 Hours)
	Microbiology 5	Corynebacterium diphtheriae Actinomyces israelii Nocardia Asteroides Nocardia Brasiliensis Mycobacterium tuberculosis Mycobacterium leprae		(2 Hour & 12 minutes)
	Microbiology 6	Neisseria meningitidis Neisseria gonorrhoeae Moraxella catarrhalis Haemophilus influenzae Haemophilus ducreyi Pasteurella multocida Francisella tularensis Bordetella pertussis Brucella Species Legionella pneumophila		(2 Hours & 41 minutes)
	Microbiology 7	Campylobacter jejuni Helicobacter pylori Vibrio cholerae Pseudomonas aeruginosa Shigella Species Yersinia pestis Yersinia Entercolitica Salmonella Species Proteus mirabilis/Proteus vulgaris		(2 Hours & 48 minutes)
	Microbiology 8	Escherichia coli Klebsiella pneumoniae Gardnerella vaginalis Bacteroides fragilis Treponema pallidum Leptospira interrogans Borrelia burgdorferi Borrelia Recurrentis		(2 Hours & 26 minutes)
	Microbiology 9	Chlamydia trachomatis Chlamydophila Rickettesia Mycoplasma pneumoniae Ureaplasma urealyticum Bartonella hensele Fungal morphology Malassezia furfur Dermatophytes Sporothrix schenckii Histoplasma capsulatum Coccidioides Immitis Blastomyces dermatitidis Paracoccidioides brasiliensis		(2 Hours & 17 minutes)
	Microbiology 10	Aspergillus Fumigates Candida albicans Cryptococcus neoformans Mucor, Rhizopus, Absidia Pneumocystis jirovecii Giardia lamblia Entamoeba histolytica Cryptosporidium Toxoplasma gondii Naegleria fowleri Trypanosoma brucei		(2 Hours & 6 minutes)
	Microbiology 11	Plasmodium (P. vivax/ovale, P. falciparum, P. malariae) Babesia Trypanosoma cruzi Leishmania donovani Trichomonas vaginalis Enterobius vermicularis Ascaris lumbricoides Strongyloides stercoralis Hookworms (Ancylostoma duodenale, Necator americanus) Trichinella spiralis Onchocerca volvulus Loa loa Wuchereria bancrofti Toxocara canis. Taenia solium Diphyllobothrium latum Echinococcus granulosus Schistosoma Clonorchis sinensis Sarcoptes scabiei Pediculus humanus/ Phthirus pubis		(2 Hours & 27 minutes)
	Microbiology 12	Nature of human viruses Parvovirus (B19) Human Papilloma Virus (HPV) BK Virus JC Virus Adenovirus HSV-1 and HSV-2 Varicella Zoster Virus (HHV-3) Epstein-Barr Virus (HHV-4) Cytomegalovirus (HHV-5) Human herpesviruses 6 and 7 HHV-8 Variola/Smallpox Molluscum contagiosum		(3 Hours)
	Microbiology 13	Norovirus Hepeviridae Enteroviruses Rhinoviruses Heparnaviruses Yellow fever Dengue virus Zika virus Chikungunya virus Rubella virus Coronavirus SARS-CoV Severe acute respiratory syndrome coronavirus Human Immunodeficiency Virus (HIV)		(3 Hours & 6 minutes)
	Microbiology 14	Measles Virus Mumps Virus Parainfluenza Respiratory syncytial virus (RSV) Rabies Virus Ebola virus Influenza virus Bunyaviridae Arenaviridae Rotavirus		(1 Hour & 44 minutes)
	Microbiology 15	Hepatitis viruses Viral genetics Penicillins β-lactamase inhibitors Cephalosporins Imipenem and Meropenem (penems) Monobactams Vancomycin		(2 Hours & 26 minutes)
	Microbiology 16			(1 Hours & 15 minutes)
	Microbiology 17	Aminoglycosides Tetracyclines Glycylcyclines Chloramphenicol Clindamycin Macrolides Oxazolidinones Sulfonamides Dapsone Trimethoprim Quinolones Metronidazole Polymyxins Rifamycins Isoniazid Pyrazinamide Ethambutol		(2 Hours & 45 minutes)
	Microbiology 18	Amphotericin B Nystatin Azoles Flucytosine Terbinafine Echinocandins Griseofulvin Antiprotozoal therapy Anthelminthic therapy Antimalarial drugs Chloroquine Anti-mite/louse therapy Acyclovir, famciclovir, valacyclovir Ganciclovir Foscarnet Cidofovir Amantadine Zanamivir and Oseltamivir Remdesivir HIV therapy Hepatitis C therapy Antibiotics to avoid in Pregnancy Antimicrobial prophylaxis		(2 Hours & 7 minutes)
Immunology			7	18 Hours
	Immunology 1	Cells of the Immune System B lymphocytes antigen receptors T lymphocytes antigen receptors The generation of receptor diversity		(2 hours & 15 mins)
	Immunology 2	Selection of B lymphocytes Selection of T lymphocytes MHC Class I molecules MHC Class II molecule Lymph nodes Spleen Antigenic determinants or epitopes Hapten Acute inflammatory response Steps in Extravasation Phagocytosis Opsonization Intracellular Killing		(1 Hour & 48 minutes)
	Immunology 3	MHC class I MHC class II HLA subtypes associated with diseases Activation of T Lymphocyte Development of the Th1, Th2, and Th17 Development of Cytotoxic T Lymphocytes Thymus Dependent-Antigen Activated B Lymphocytes Thymus Independent-Antigen Activated B Lymphocytes Isotype switching Somatic hypermutation Humoral immunity The primary humoral response Antibodies of secondary immune responses		(2 Hours & 36 minutes)
	Immunology 4	Complement Activation of macrophages Activation of cytotoxic T lymphocytes Activation of natural killer cells Antibody-dependent cell-mediated cytotoxicity Interferons Cytokines Vaccination and Immunotherapy		(2 Hours & 31 minutes)
	Immunology 5	Type I (immediate) hypersensitivity Type II hypersensitivity Type III (immune complexes) Hypersensitivity Type IV (T-cell mediated) Hypersensitivity Blood transfusion reactions		(2 Hours)
	Immunology 6	X-linked (Bruton) agammaglobulinemia Selective IgA deficiency Common variable immunodeficiency Transient hypogammaglobulinemia of infancy Thymic aplasia (DiGeorge syndrome) IL-12 receptor deficiency Autosomal dominant hyper-IgE syndrome (Job syndrome) Chronic mucocutaneous candidiasis MHC Class I Deficiency Severe combined immunodeficiency (SCID) Ataxia-telangiectasia Hyper-IgM syndrome Wiskott-Aldrich syndrome Bare Lymphocyte Syndrome/MHC class II deficiency Leukocyte adhesion deficiency (type 1) Chédiak-Higashi syndrome Chronic granulomatous disease		(2 Hours & 28 minutes)
	Immunology 7	Hyperacute rejection Acute rejection Chronic rejection Graft-versus-host disease (GVHD) Cyclosporine Tacrolimus (FK506) Sirolimus (Rapamycin) Daclizumab, basiliximab Azathioprine Mycophenolate, Mofetil Glucocorticoids		(1 Hour & 20 minutes)
Biochemistry			17	40 Hours
	Biochemistry 1	Cell cycle phases Regulation of cell cycle Nucleotide structure and nomenclature DNA structure Chromatin structure		(1 Hour & 52 minutes)
	Biochemistry 2	DNA Replication Comparison of DNA and RNA synthesis Mutations in DNA Base substitutions (point mutations) Frameshift mutations DNA Repair		(2 Hours & 15 minutes)
	Biochemistry 3	RNA Transcription RNA polymerases Production of Eukaryotic mRNA Processing of Eukaryotic Pre-Messenger RNA Alternative splicing of Eukaryotic primary pre-mRNA transcript Regulation of gene expression Lac operon		(1 Hour & 51 minutes)
	Biochemistry 4	tRNA Genetic code features Protein Translation Posttranslational modifications Chaperone protein Proteasomes and Ubiquitin		(1 Hour & 31 minutes)
	Biochemistry 5	Rough endoplasmic reticulum Smooth endoplasmic reticulum Cell trafficking Collagen synthesis and structure Osteogenesis Imperfecta Ehlers-Danlos syndrome Menkes disease Elastin Marfan syndrome Microtubule Cilia structure		(2 Hours & 24 minutes)
	Biochemistry 6	Producing Restriction Fragments: Restriction Endonucleases Blotting techniques Polymerase chain reaction Molecular cloning Flow cytometry CRISPR/Cas9 Microarrays Karyotyping A Fluorescence in situ hybridization Enzyme-linked immunosorbent assay Gene expression modifications		(2 Hours & 10 minutes)
	Biochemistry 7	Genetic terms Autosomal dominant Autosomal recessive X-linked recessive X-linked dominant Mitochondrial inheritance X inactivation		(2 Hours & 51 minutes)
	Biochemistry 8	Variable expressivity Incomplete penetrance Loss of heterozygosity Pleiotropy Anticipation Dominant negative mutation Locus heterogeneity Allelic heterogeneity Heteroplasmy Imprinting Uniparental disomy Mosaicism Linkage disequilibrium		(2 Hours & 30 minutes)
	Biochemistry 9	Autosomal dominant diseases Autosomal recessive diseases Cystic fibrosis X-linked recessive disorders Muscular dystrophies Duchenne muscular dystrophy (DMD) Becker muscular dystrophy Myotonic type 1 Fragile X syndrome Trinucleotide repeat expansion diseases Numerical chromosome abnormalities Down syndrome (trisomy 21) Edwards syndrome (trisomy 18) Patau syndrome (trisomy 13) Translocation Deletions		(2 Hours & 22 minutes)
	Biochemistry 10	Hardy-Weinberg population genetics Genetic diagnosis Paternity testing		(2 Hours & 40 minutes)
	Biochemistry 11	Glycolysis Galactose metabolism Galactokinase deficiency Classic galactosemia Sorbitol Fructose metabolism Essential fructosuria Hereditary fructose intolerance		(2 Hours & 25 minutes)
	Biochemistry 12	Pyruvate dehydrogenase Pyruvate dehydrogenase complex deficiency Pyruvate metabolism Citric acid cycle Electron transport chain and oxidative phosphorylation Gluconeogenesis		(2 Hours & 26 minutes)
	Biochemistry 13	Glycogen metabolism Glycogenesis Glycogenolysis Glycogen storage diseases Hexose monophosphate shunt Glucose-6-phosphate dehydrogenase deficiency ATP production Universal electron acceptors		(2 Hours & 5 minutes)
	Biochemistry 14	Fatty acid synthesis Triglyceride synthesis Lipid mobilization Key enzymes in lipid transport Lipoprotein functions Abetalipoproteinemia Familial dyslipidemias		(3 Hours & 21 minutes)
	Biochemistry 15	Fatty acid oxidation Systemic primary carnitine deficiency Medium chain acyl-CoA dehydrogenase (MCAD) deficiency Peroxisomal diseases Ketone bodies metabolism Sphingolipids Lysosomal storage diseases Sphingolipidoses Mucopolysaccharidoses		(2 Hours & 3 minutes)
	Biochemistry 16	Amino acid metabolism Urea cycle Hyperammonemia Ornithine transcarbamylase deficiency Amino acids Protein structure Amino acid derivatives Catecholamine synthesis/tyrosine catabolism Phenylketonuria Maple syrup urine disease Alkaptonuria Homocystinuria Metabolic fuel use		(2 Hours & 33 minutes)
	Biochemistry 17	Pyrimidine synthesis Orotic aciduria Purine synthesis Purine salvage pathway Adenosine deaminase deficiency Lesch-Nyhan syndrome Water soluble vitamins Fat soluble vitamins Protein-energy malnutrition Ethanol metabolism		(2 Hours & 31 minutes)
General Pathology			2	(5 Hours & 20 minutes)
	General Pathology 1	Cell injury Necrosis Apoptosis Types of calcification Ischemia Infarcts: red vs pale Free radical injury Inflammation Erythrocyte sedimentation rate Exudate vs transudate		(2 Hours & 30 minutes)
	General Pathology 2	Leukocyte extravasation Wound healing Scar formation Lipofuscin Amyloidosis Cellular adaptations Neoplasia and neoplastic progression Tumor nomenclature Tumor grade vs stage Hallmarks of cancer Immune checkpoint interactions Cancer epidemiology Common metastases Oncogenes Tumor suppressor genes Carcinogens Oncogenic microbes Serum tumor markers Important immunohistochemical stains P-glycoprotein Psammoma bodies Cachexia Paraneoplastic syndromes		(2 Hours & 45 minutes)
General Pharmacology			4	(11 Hours & 30 minutes)
	General Pharmacology 1	Permeation Absorption Distribution Biotransformation		(2 Hours & 25 minutes)
	General Pharmacology 2	Elimination Michaelis-Menten Equation Lineweaver-Burk Equation Full and Partial Agonists Duality of Partial Agonists Antagonism and Potentiation Pharmacologic antagonism Toxicity and the Therapeutic Index (TI) Types of drug interactions		(3 Hour & 15 minutes)
	General Pharmacology 3	Anatomy of the ANS Location of ANS Ganglia Neurotransmitters ACh receptors Drug Receptors Linked Via Coupling Proteins to Intracellular Effectors G-protein–linked second messengers Cholinomimetic agents Anticholinesterase poisoning Muscarinic antagonists Atropine		(2 Hours & 56 minutes)
	General Pharmacology 4	Sympathomimetics Physiologic effects of sympathomimetics Sympatholytics (α2-agonists) α-blockers β-blockers Phosphodiesterase inhibitors Ingested seafood toxins Beers criteria		(3 Hours & 20 minutes)
Cardiovascular System			15	38 Hours
	Cardiovascular 1	Development of the Heart Septation of the Atria Septation of Ventricles Septation of the Truncus Arteriosus Heart embryology Fetal circulation Aortic arch derivatives		(2 Hours & 35 minutes)
	Cardiovascular 2	Surface Projections of the Heart Pericardium Arterial Supply of the Heart Diaphragm Imaging		(2 Hour & 51 minutes)
	Cardiovascular 3	Cardiac output Mean arterial pressure (MAP) Cardiac output variables Stroke volume Contractility Preload Afterload Ejection fraction Wall tension		(2 Hours & 45 minutes)
	Cardiovascular 4	Ventricular function curves Starling curve Cardiac and vascular function curves Normal Cardiac Cycle		(2 Hours & 24 minutes)
	Cardiovascular 5	Heart sounds Systemic venous pulse Pressure- volume loops Pulmonary wedge pressure		(2 Hours & 32 minutes)
	Cardiovascular 6	Mitral/Tricusped Regurgitation Aortic Stenosis Mitral Valve Prolapse Ventricular Septal Defect (VSD) Aortic Regurgitation Mitral Stenosis Patent Ductus Arteriosus		(2 Hours and 35 minutes)
	Cardiovascular 7	Auscultation of the heart Nervous reflexes in the control of blood pressure Natriuretic peptides Autoregulation of systemic blood flow Capillary fluid exchange Cardiac conduction system		(2 Hours & 19 minutes)
	Cardiovascular 8	The Ventricular Action Potential Pacemaker action potential Physiology of ECG		(2 Hours & 25 minutes)
	Cardiovascular 9	Pathology of ECG< Atrial fibrillation Atrial flutter Ventricular fibrillation AV block Congenital long QT syndrome Torsades de pointes Brugada syndrome Wolff-Parkinson-White syndrome		(2 Hours & 38 minutes)
	Cardiovascular 10	Persistent truncus arteriosus D-transposition of great vessels Tricuspid atresia Tetralogy of Fallot Total anomalous pulmonary venous return Ventricular septal defect Atrial septal defect Patent ductus arteriosus Coarctation of the aorta Ebstein anomaly Congenital cardiac defect associations Hypertension Renal artery stenosis Isolated systolic hypertension (ISH)		(2 Hour & 33 minutes)
	Cardiovascular 11	Atherosclerosis Hyaline arteriolosclerosis Hyperplastic arteriolosclerosis Monckeberg medial calcific sclerosis Hyperlipidemia signs Aortic dissection Aortic aneurysm Abdominal aortic aneurysm Traumatic aortic rupture Angina Coronary steal syndrome Myocardial infarction		(2 Hours & 49 minutes)
	Cardiovascular 12	Evolution of myocardial infarction Diagnosis of myocardial infarction ECG localization of STEMI Sudden cardiac death (SCD) Chronic ischemic heart disease Dilated cardiomyopathy Hypertrophic cardiomyopathy Restrictive/infiltrative cardiomyopathy Left-sided heart failure Right- sided heart failure		(2 Hours & 26 minutes)
	Cardiovascular 13	Shock Rheumatic fever Bacterial endocarditis Myocarditis Acute pericarditis Cardiac tamponade Myxomas Rhabdomyomas Metastasis		(2 Hours & 32 minutes)
	Cardiovascular 14	Temporal (Giant Cell) Arteritis Takayasu Arteritis Polyarteritis Nodosa Kawasaki Disease Buerger Disease (thromboangiitis obliterans) Granulomatosis with polyangiitis (Wegener) Microscopic Polyangiitis Eosinophilic granulomatosis with polyangiitis (Churg-Strauss Syndrome) Henoch-Schönlein Purpura (Immunoglobulin A vasculitis) Mixed cryoglobulinemia Behçet syndrome Calcium channel blockers (CCBs) α1 blockers Central α2 agonists Direct acting vasodilators Hypertensive emergency		(2 Hours & 35 minutes)
	Cardiovascular 15	Nitrate Ranolazine Digoxin Phosphodiesterase inhibitors Sympathomimetics: dobutamine and dopamine Sacubitril HMG-CoA reductase inhibitors Bile acid sequestrants Gemfibrozil, Fenofibrate (fibrates) Niacin Ezetimibe PCSK9 inhibitors Fish oil and marine omega-3 fatty acids Sodium channel blockers (class I) β-blockers (class II) Potassium channel blockers (class III) Calcium channel blockers (class IV) Unclassified antiarrythmic		(3 Hours & 30 minutes)
Respiratory System			9	26 Hours
	Respiratory 1	Lung development Conducting zone Respiratory zone Lobes and fissures Lymphatic drainage of the lung Pneumocytes Congenital lung malformations Pleura Pleural recesses Thoracentesis Chest tube insertion		(2 Hour & 58 minutes)
	Respiratory 2	Lung volumes and capacities Pulmonary Function Testing Obstructive versus Restrictive Patterns Volume loops Dead space Alveolar Ventilation Lung mechanics		(2 Hours & 58 minutes)
	Respiratory 3	Positive Pressure Ventilation Lung Compliance Inflation Curves Pulmonary circulation Gas exchange in the lung Diffusion Capacity of the lung DLco Perfusion-Limited vs. Diffusion-Limited Factors Determining Alveolar PCO2 Factors Determining Alveolar PO2		(2 Hours & 19 minutes)
	Respiratory 4	Carbon Dioxide Transport Oxygen Transport Bohr and Haldane effect Oxygen-Hb Dissociation Curves Carbon Monoxide Poisoning Neural regulation of alveolar ventilation Muscles of Respiration		(2 Hours & 27 minutes)
	Respiratory 5	Hypoxemia due to High Altitude Hypoxemia due to Hypoventilation Hypoxemia due to Diffusion Impairment Hypoxemia due to Pulmonary Shunt Hypoxemia due to Ventilation-Perfusion mismatch VA/Q Mismatches Response to exercise Hyperbaric Environment		(3 Hours & 7 minutes)
	Respiratory 6	Rhinosinusitis Epistaxis Nasal polyps Angiofibroma Nasopharyngeal carcinoma Acute epiglottitis Laryngotracheobronchitis (croup) Vocal cord nodules (singer's nodules) Laryngeal papilloma Laryngeal carcinoma Pneumonia Lung abscess		(2 Hours)
	Respiratory 7	Tuberculosis (TB) Deep venous thrombosis Pulmonary emboli Chronic bronchitis (blue bloaters) Emphysema (pink puffer) Asthma Bronchiectasis		(3 Hours & 13 minutes)
	Respiratory 8	Restrictive diseases Pulmonary fibrosis Pneumoconiosis Hypersensitivity pneumonitis Sarcoidosis Acute respiratory distress syndrome Neonatal respiratory distress syndrome Primary pulmonary hypertension Secondary pulmonary hypertension Obstructive sleep apnea Central sleep apnea Obesity hypoventilation syndrome		(3 Hours & 29 minutes)
	Respiratory 9	Small cell lung carcinoma Lung Adenocarcinoma Squamous cell carcinoma Large cell carcinoma Bronchial carcinoid tumor Pancoast syndrome (superior sulcus tumor) Superior vena cava syndrome Pneumothorax Pleural effusions Mesothelioma Mediastinal masses Mediastinitis Pneumomediastinum Atelectasis Antihistamines Expectorants Dextromethorphan Pseudoephedrine, phenylephrine Treatment of pulmonary hypertension Asthma drugs		(3 Hours & 41 minutes)
Endocrinology			9	25 Hours
	Endocrinology 1	Pharyngeal apparatus Branchial arch derivatives Branchial pouch derivatives Pharyngeal grooves (clefts) Thyroid gland Lingual thyroid Thyroglossal cyst Thyroglossal fistula DiGeorge syndrome (22q11 deletion)		(1 Hour & 50 minutes)
	Endocrinology 2	Hypothalamic – Anterior Pituitary System Pituitary gland Growth Hormone Gigantism Acromegaly Pituitary dwarfism Prolactin Pituitary adenoma Hyperprolactinemia Craniopharyngioma Sheehan's Syndrome Pituitary Apoplexy Empty Sella syndrome		(2 Hours & 54 minutes)
	Endocrinology 3	Posterior Pituitary Antidiuretic Hormone (vasopressin) Diabetes Insipidus Primary (Psychogenic) Polydipsia Syndrome of inappropriate antidiuretic hormone secretion (SIADH) Oxytocin Adrenal Gland Physiological effect of cortisol (glucocorticoid) Physiologic action of aldosterone Juxtaglomerular Apparatus Renin-Angiotensin-Aldosterone System Physiologic action of androgens and estrogens		(3 Hours & 1 minutes)
	Endocrinology 4	Cushing syndrome Adrenal insufficiency Adrenal crisis Primary hyperaldosteronism (Conn’s syndrome) Secondary hyperaldosteronism Congenital adrenal hyperplasia Pheochromocytoma Neuroblastoma		(3 Hours & 12 minutes)
	Endocrinology 5	Thyroid hormones Physiologic action of thyroid hormones Regulation of thyroid hormones Hashimoto's thyroiditis Subacute thyroiditis (de Quervain's thyroiditis) Riedel thyroiditis Congenital Hypothyroidism (cretinism) Postpartum thyroiditis Grave's disease Toxic multinodular goiter Thyroid storm Jod-Basedow phenomenon Thyroid adenoma Papillary carcinoma Follicular carcinoma Medullary carcinoma Undifferentiated/anaplastic carcinoma		(3 Hours & 54 minutes)
	Endocrinology 6	Calcium hemostasis Parathyroid hormone Calcitonin Vitamin D (cholecalciferol) Primary hyperparathyroidism Secondary hyperparathyroidism Tertiary hyperparathyroidism Familial hypocalciuric hypercalcemia Milk-alkali syndrome (MAS) Hypocalcemia Pseudohypoparathyroidism type 1A Pseudopseudohypoparathyroidism		(2 Hours & 33 minutes)
	Endocrinology 7	Pancreas Insulin Glucagon Diabetes mellitus Complication of diabetes mellites Diabetic Ketoacidosis Hyperosmolar hyperglycemic state (HHS) Hypoglycemia Infant of diabetic mother Metabolic Syndrome (Syndrome X)		(3 Hours & 14 minutes)
	Endocrinology 8	Insulinoma Zollinger-Ellison syndrome (gastrinoma) Glucagonoma Somatostatinoma Neuroendocrine tumors Multiple Endocrine Neoplasia Ghrelin Leptin Endocannabinoids Signaling pathways of endocrine hormones		(3 Hours & 2 minutes)
	Endocrinology 9	Insulin preparations Biguanides (Metformin) Sulfonylureas Glitazones/thiazolidinediones GLP-1 analogs DPP-4 inhibitors Alpha-glucosidase inhibitors SGLT-2 inhibitors Amylin analogs Thionamides Radioactive iodine Levothyroxine (T4), liothyronine (T3) Hypothalamic/pituitary drugs Demeclocycline Glucocorticoids Fludrocortisone Cinacalcet Sevelamer		(2 Hours & 50 minutes)
Nephrology			10	28 Hours
	Nephrology 1	Embryonic kidney development Unilateral renal agenesis Multicystic dysplastic kidney Duplex collecting system Posterior urethral valves (PUV) Amniotic fluid (AF) Potter syndrome The urachus Horseshoe kidney Physiologic anatomy of the kidney Renal blood flow Nephron Ureter		(2 Hours & 43 minutes)
	Nephrology 2	Overview of renal function Fluid compartments Formation of urine Renal blood flow Glomerular filtration barrier Glomerular filtration rate (GFR) Filtration Fraction (FF) Filtered Load		(2 Hours & 54 minutes)
	Nephrology 3	Renal clearance Renal transport and clearance Reabsorption Secretion		(2 Hours & 34 minutes)
	Nephrology 4	Proximal Tubule transport Loop of Henle transport Early Distal Tube transport Late Distal Tubule and Collecting Duct transport Hydrogen Secretion and Acidification of the Urine		(3 Hours)
	Nephrology 5	Pathophysiology of Potassium Dynamics Electrolyte disturbances Kidney endocrine functions		(2 Hours & 18 minutes)
	Nephrology 6	Acid base disturbance Determining a Primary Problem Plasma Anion Gap Contraction alkalosis Compensatory mechanisms Davenport Diagram		(2 Hours & 30 minutes)
	Nephrology 7	Acute poststreptococcal glomerulonephritis Diffuse proliferative glomerulonephritis (DPGN) IgA nephropathy (Berger disease) Alport syndrome Rapidly progressive (crescentic glomerulonephritis (RPGN) Minimal change disease (lipoid nephrosis) Focal segmental glomerulosclerosis (FSGS) Membranous nephropathy Membranoproliferative glomerulonephritis (MPGN) Amyloidosis Diabetic glomerulonephropathy		(3 Hours & 29 minutes)
	Nephrology 8	Nephrolithiasis Hydronephrosis Vesicoureteral reflux Stress Incontinence Urge (Hypertonic) Incontinence Overflow (Hypotonic) Incontinence Cystitis Pyelonephritis		(3 Hours & 16 minutes)
	Nephrology 9	Acute kidney injury Acute tubular necrosis Diffuse cortical necrosis Acute interstitial nephritis Chronic interstitial nephritis Renal papillary necrosis Chronic Renal Failure Cardiorenal syndrome Fanconi Syndrome Bartter syndrome Gitellman syndrome Liddle syndrome Syndrome of Apparent Mineralocorticoid Excess		(2 Hours & 47 minutes)
	Nephrology 10	Renal tubular acidosis Autosomal dominant polycystic kidney disease Autosomal recessive polycystic kidney disease Autosomal dominant tubulointerstitial kidney disease Simple vs complex renal cysts Atheroembolic renal disease Renal cell carcinoma Renal oncocytoma Wilms tumor Lower urinary tract carcinoma Urothelial (Transitional) cell carcinoma Squamous cell carcinoma of the bladder Mannitol Acetazolamide Loop diuretics Ethacrynic acid Thiazide diuretics Potassium-sparing diuretics Electrolyte changes associated with the use of diuretics Angiotensin converting enzyme inhibitors Angiotensin II receptor blockers Aliskiren		(3 Hours & 35 minutes)
Reproductive System			12	30 Hours
	Reproductive 1	Early fetal development Embryologic derivatives Sonic hedgehog (SHH) gene Fibroblast growth factor (FGF) gene Wnt-7 gene Homeobox (Hox) genes Types of errors in organ morphogenesis Teratogens Fetal alcohol syndrome Fetal hydantoin syndrome Neonatal abstinence syndrome		(3 Hours & 15 minutes)
	Reproductive 2	Gonad development Uterine (Müllerian duct) anomalies Hypospadias Epispadias Descent of testes and ovaries Twinning Placenta Umbilical cord		(2 Hours & 18 minutes)
	Reproductive 3	Gonadal drainage Female reproductive anatomy Pouches of pelvis Female reproductive epithelial histology Male reproductive anatomy Retrograde ejaculation Urethral injury Penis Anatomy Autonomic innervation of the male sexual response		(2 Hours & 24 minutes)
	Reproductive 4	Oogenesis The menstrual cycle Monitoring the Menstrual Cycle Estrogen Progesterone		(2 Hours & 22 minutes)
	Reproductive 5	Pregnancy hCG (Human chorionic gonadotropin) hPL (Human Placental Lactogen) Hormonal changes during pregnancy Physiologic Adaptations to Pregnancy Apgar score Low birth weight Lactation Menopause Spermatogenesis Organization of the Testes Seminiferous tubules Androgens Tanner stages of sexual development Precocious puberty		(2 Hours & 58 minutes)
	Reproductive 6	Klinefelter syndrome [male] (47, XXY) Turner syndrome [female] (45, XO) Double Y males (XYY) Ovotesticular disorder of sex development Other disorders of sex development Androgen insensitivity syndrome (46, XY) 5α-reductase deficiency Placental aromatase deficiency Kallmann syndrome Vulvar pathology Vaginal Adenosis Clear cell adenocarcinoma Sarcoma botryoides (Embryonal rhabdomyosarcoma) Vaginal squamous cell carcinoma		(2 Hours & 50 minutes)
	Reproductive 7	Cervical intraepithelial neoplasia Cervical carcinoma Acute endometritis Chronic endometritis Asherman syndrome Abnormal uterine bleeding Anovulatory cycle Endometrial polyp Endometriosis Adenomyosis Primary dysmenorrhea Secondary dysmenorrhea Leiomyoma (fibroids) Leiomyosarcoma Endometrial hyperplasia Endometrial carcinoma		(3 Hours & 23 minutes)
	Reproductive 8	Polycystic ovarian syndrome (PCOS) Ovarian tumors Ovarian cysts Ovarian torsion Amenorrhea Functional hypothalamic amenorrhea		(2 Hours & 53 minutes)
	Reproductive 9	Ectopic Pregnancy Spontaneous abortion Placental abruption (abruptio placentae) Placenta previa Vasa previa Placenta accreta/increta/percreta Postpartum hemorrhage Gestational hypertension (pregnancy-induced hypertension) Preeclampsia Eclampsia HELLP syndrome		(2 Hours & 23 minutes)
	Reproductive 10	Gestational Trophoblastic disease (GTD) Choriocarcinoma Polythelia Lactational mastitis Fat necrosis Fibrocystic Breast Changes Fibroadenoma Intraductal papilloma Phyllodes tumor Noninvasive Breast carcinomas Invasive Breast carcinomas Prognostic and predictive factors of breast cancer Prognostic and predictive factors Male breast cancer Gynecomastia		(2 Hours & 49 minutes)
	Reproductive 11	Peyronie disease Ischemic priapism Squamous cell carcinoma Epididymitis and orchitis Testicular torsion Varicocele Cryptorchidism Congenital Hydrocele Acquired hydrocele Spermatocele Testicular tumors Extragonadal germ cell tumors Prostatitis Benign prostatic hyperplasia (BPH) Prostate adenocarcinoma		(2 Hours & 59 minutes)
	Reproductive 12	Goserelin, Leuprolide Degarelix Estrogen drugs Selective estrogen receptor modulators Aromatase inhibitors Hormone replacement therapy Progestins Antiprogestins Combined contraception Copper intrauterine device Tocolytics Danazol Testosterone, methyltestosterone Antiandrogens Tamsulosin Phosphodiesterase type 5 inhibitors Minoxidil		(2 Hours & 31 minutes)
Neurology			16	39 Hours
	Neurology 1	Nervous System Development Neural tube Defects Anencephaly Holoprosencephaly Lissencephaly Spina bifida occulta (hidden) Spina bifida cystica (Aperta) Spina bifida with myeloschisis Arnold chiari malformation Dandy walker malformation		(2 Hour & 37 minutes)
	Neurology 2	Spinal nerves Motor system Muscle tone Reflex innervation of skeletal muscle Clinical reflexes Dorsal column – medial lemniscal pathway Anterolateral (spinothalamic tract) pathway Sectional anatomy of the spinal cord Oculosympathatic pathway		(3 Hours)
	Neurology 3	Brown sequard syndrome Poliomyelitis Spinal muscular atrophy (Werding – Hoffman disease) Tabes dorsalis Amyotrophic lateral sclerosis (lou Gehrig’s disease) Anterior spinal artery ( ASA ) occlusion Subacute combined degeneration (SCD) Syringomyelia Cauda Equina Syndrome Dermatomes		(2 Hours & 26 minutes)
	Neurology 4	Course of neural systems in brain stem Brain stem cut sections Cranial Nerve I (Olfactory Nerve) Cranial Nerve II (Optic Nerve) Visual field defects Pupillary Light Reflex Marcus gunn pupil (Relative Afferent pupillary Defect)		(2 Hours & 27 minutes)
	Neurology 5	Cranial Nerve III (Oculomotor nerve) Accommodation-Convergence Reaction (Near Response) Argyl Robertson pupil Adie’s pupil Cranial Nerve IV (Trochlear Nerve, SO4) Cranial Nerve V (Trigiminal Nerve) Corneal Reflex (Blink reflex) Trigeminal neuralgia Cranial Nerve VI (Abducens Nerve, LR6) Cranial Nerve VII (Facial nerve) Cranial Nerve VIII (Vestibulochochlear Nerve) Sound processing Hearing Loss Cholesteatoma Presbycusis Hyperacusis		(2 Hours & 44 minutes)
	Neurology 6	Vestibulo-ocular Reflex Vestibular evoked nystagmus (in vestibular nerve or nucleus lesion) Tests for Nystagmus Central vertigo Benign paroxysmal positional vertigo (BPPV) Ménière disease Labyrinthitis Voluntary horizontal conjugate gaze Cranial Nerve IX (Glossopharyngeal Nerve) Cranial Nerve X (Vagus Nerve) Gag reflex (pharyngeal reflex) Cranial Nerve VI (Accessory Nerve) Cranial Nerve VII (Hypoglossal Nerve)		(2 Hours)
	Neurology 7	Medial medullary syndrome Lateral medullary (Wallenberg) syndrome Medial pontine syndrome Lateral pontine syndrome Medial midbrain syndrome Dorsal midbrain (parinaud) syndrome Cranial nerves and vessel pathway Jugular foramen (Vernet) syndrome Cranial nerve reflexes Common cranial nerve lesions Innervation of the tongue Cavernous sinus Cerebellum Cerebellar lesions Friedreich Ataxia		(2 Hours & 52 minutes)
	Neurology 8	Basal Ganglia Parkinson disease Huntington disease Wilson disease (hepatolenticular degeneration) Hemibalsmus Types of tremors Thalamus Thalamic syndrome Hypothalamus Subthalamus Epithalamus Noncommunicating (Obstructive) hydrocephalus Communicating hydrocephalus Normal pressur hydrocephalus Hydrocephalus ex vacuo Pseudotumor cerebri		(2 Hours & 50 minutes)
	Neurology 9	Homunculus of the cerebral cortex Frontal lobe Parietal lobe Temporal lobe Aphasia Occipital lobe Blood supply of the cerebral cortex Effects of strokes Anterograde amnesia Korsakoff-syndrome Kluver-bucy syndrome		(3 Hours & 25 minutes)
	Neurology 10	Neurons Astrocytes Microglia Ependymal cells Wallerian Degeneration Sensory receptors Neurotransmitter changes with disease Meninges Blood-brain barrier Vomiting center Dopaminergic pathways Regulation of cerebral perfusion		(2 Hours & 23 minutes)
	Neurology 11	Alzheimer disease Frontotemporal dementia (pick’s disease) Lewy body dementia Creutzfeldt-jakob disease Vascular dementia Multiple Sclerosis Guillan-Barre syndrome Osmotic demyelination syndrome Acute disseminated (postinfectious) encephalomyelitis HSV 1 encephalitis Progressive multifocal leukoencephalopathy (PML) Charcot-Marie-Tooth disease Epidural hematoma Subdural hematoma Subarachnoid hemorrhage (SAH) Intraparenchymal (hypertensive) hemorrhage Saccular (Berry) aneurysm Neonatal intraventricular hemorrhage		(3 Hours & 25 minutes)
	Neurology 12	Diffuse axonal injury Strokes Transient ischemic attack (TIA) Subclavian steal syndrome Cluster headache Migraine headache Tension headache Fever vs heat stroke Sturge-Weber syndrome Tuberous sclerosis Neurofibromatosis type 1 (Von Recklinghausen disease) Neurofibromatosis type II Von Hippel-Lindau disease		(3 Hours & 4 minutes)
	Neurology 13	Adult primary brain tumors Childhood primary brain tumors Herniation syndromes Diabetic Neuropathy Diabetic ophthalmoplegia Conjunctivitis Refractive errors Presbyopia Cataract Glaucoma Glaucoma drugs		(3 Hours & 25 minutes)
	Neurology 14	Uveitis Age-related macular degeneration (AMD) Diabetic retinopathy Hypertensive retinopathy Central retinal artery occlusion Central Retinal vein occlusion Retinal detachment Retinitis pigmentosa Retinitis Papilledema Leukocoria Opioid Analgesic Tramadol		(3 Hours & 3 minutes)
	Neurology 15	Types of seizures Antiepileptic drugs Status Epilepticus Sedative – hypnotic – anxiolytic drugs Nonbenzodiazepine hypnotics Suvorexant Ramelteon		(2 Hours & 15 minutes)
	Neurology 16	General principles of anesthesia Inhaled anesthetics Malignant hyperthermia Intravenous anesthetics Local anesthetics Neuromuscular blocking drugs Dantrolene Baclofen Cyclobenzaprine Tizanidine Parkinson disease drugs Alzheimer drugs Huntington disease drugs Triptans (Sumatriptan)		(2 Hours & 34 minutes)
Musculoskeletal System			13	28 Hours
	Musculoskeletal System 1	Cleft lip and cleft palate Congenital torticollis Brachial plexus Axillary (C5-C6) Musculocutaneous (C5-C7) Radial (C5-T1)		(2 Hour & 36 minutes)
	Musculoskeletal System 2	Median (C5-T1) Recurrent branch of median nerve (C5-T1) Ulnar (C8-T1) Segmental Innervation to Muscles of Upper Limbs Erb palsy (waiter’s tip) Klumpke palsy Thoracic outlet syndrome Winged scapula		(2 Hours & 38 minutes)
	Musculoskeletal System 3	Rotator cuff muscles Anterior dislocation of the shoulder Rotator cuff syndrome Clavicular fracture Lateral epicondylitis Medial epicondylitis Wrist bones Lunate dislocation Scaphoid fractures Metacarpal neck fracture Distortions of the hand Hand muscles Carpal tunnel syndrome Guyon canal syndrome Lumbosacral plexus Iliohypogastric Genitofemoral nerve Lateral femoral cutaneous Obturator		(2 Hours & 55 minutes)
	Musculoskeletal System 4	Femoral Common peroneal (fibular) nerve Tibial Superior gluteal Inferior gluteal Pudendal Avascular necrosis of femoral head Compartment syndrome Medial collateral ligament (MCL) tear Anterior cruciate ligament (ACL) injury Meniscal tear Unhappy triad		(3 Hours & 20 minutes)
	Musculoskeletal System 5	Greater trochanteric pain syndrome (Trochanteric bursitis) Prepatellar bursitis "housemaid's knee" Baker cyst Patellar fracture Ankle joint Neurovascular pairing Lumbosacral radiculopathy Sciatica Piriformis syndrome Lumbar Spinal Stenosis Organization of a Muscle Cell Types of skeletal muscle fibers Muscle proprioceptors Sarcomere (Skeletal and Cardiac Muscle)		(2 Hours & 35 minutes)
	Musculoskeletal System 6	Organization of a Muscle Cell Types of skeletal muscle fibers Muscle proprioceptors Sarcomere (Skeletal and Cardiac Muscle) The neuron action potential Absolute Refractory Period (Functional Refractory Period) Factors Determining the Velocity of the Action Potential The Neuromuscular Junction Excitatory Postsynaptic Potentials (EPSP) Inhibitory Postsynaptic Potentials (IPSP) Skeletal and Cardiac Muscle Smooth Muscle Excitation contraction coupling (Skeletal Muscle)		(3 Hours & 16 minutes)
	Musculoskeletal System 7	Bone formation Bone matrix Endochondral ossification Membranous ossification Osteoblast Osteoclast Osteocytes De Quervain tenosynovitis Ganglion cyst Iliotibial band syndrome Medial tibial stress syndrome Patellofemoral syndrome Plantar fasciitis		(2 Hours & 9 minutes)
	Musculoskeletal System 8	Developmental dysplasia of the hip Legg-Calvé-Perthes disease Slipped capital femoral epiphysis Osgood-Schlatter disease (traction apophysitis) Radial head subluxation Greenstick fracture Torus (buckle) fracture Achondroplasia Osteoporosis Osteopetrosis (marble bone disease) Rickets/osteomalacia Paget disease of bone (osteitis deformans) Osteomyelitis		(3 Hours & 21 minutes)
	Musculoskeletal System 9	Bone tumors Degenerative joint disease (osteoarthritis) Rheumatoid arthritis Psoriatic arthritis Ankylosing spondylitis Inflammatory bowel disease Reactive arthritis Gout Pseudogout Septic arthritis		(3 Hours & 37 minutes)
	Musculoskeletal System 10	Sjogren syndrome Systemic lupus erythematosus Drug induced lupus Antiphospholipid syndrome Mixed connective tissue disease Systemic juvenile idiopathic arthritis Polymyositis/Dermatomyositis Polymyalgia Rheumatica Fibromyalgia Myasthenia gravis Lambert-Eaton syndrome Scleroderma (systemic sclerosis) Raynaud phenomenon		(3 Hours & 9 minutes)
	Musculoskeletal System 11	Skin Atopic (eczematous) dermatitis Contact dermatitis Acne vulgaris Rosacea Psoriasis Lichen planus Pemphigus valgaris Bullous pemphigoid Dermatitis herpatiformis Erythema multiforme Stevens-Johnson syndrome		(2 Hours & 53 minutes)
	Musculoskeletal System 12	Vitiligo Albinism Freckle (ephelis) Lentigo Melasma (Chloasma) Nevus (mole) Melanoma Impetigo Erysipelas Cellulitis Necrotizing fasciitis Skin abscess Staphylococcal scalded skin syndrome Verruca (wart) Molluscum contagiosum Angiosarcoma Bacillary angiomatosis Kaposi sarcoma Cherry hemangioma Strawberry hemangioma Cystic hygroma Glomus tumor Pyogenic granuloma		(2 Hours & 15 minutes)
	Musculoskeletal System 13	Acanthosis nigricans Actinic keratosis Erythema nodosum Urticaria (hives) Pityriasis rosea Pseudofolliculitis barbae Sunburn Burn Seborrheic keratosis Basal cell carcinoma Squamous cell carcinoma Aspirin NSAIDs Celecoxib Acetaminophen Leflunomide TNF-α inhibitors Bisphosphonates Teriparatide Gout drugs		(3 Hours & 46 minutes)
Hematology & Oncology			9	27 Hours
	Hematology & Oncology 1	Fetal erythropoiesis Hemoglobin development Primary hemeostasis Immune thrombocytopenic purpura (ITP) Microangiopathic hemolytic anemia Qualitative platelet disorders		(2 Hours & 56 minutes)
	Hematology & Oncology 2	Hemophilia A Hemophilia B (Christmas disease) Coagulation factor inhibitor Vitamin k deficiency Von willbrand disease Disseminated intravascular coagulation (DIC) Protein C or S deficiency Factor V Leiden Prothrombin gene mutation Antithrombin deficiency Iron deficiency anemia		(3 Hours & 24 minutes)
	Hematology & Oncology 3	Sideroblastic anemia Lead poisoning Thalassemia Megaloblastic anemia Nonmegaloblastic anemia		(2 Hours & 55 minutes)
	Hematology & Oncology 4	Hereditary spherocytosis Sickle cell anemia Paroxysmal nocturnal hemoglobinuria Glucose 6 phosphate dehydrogenase deficiency Autoimmune hemolytic anemia Microangiopathic hemolytic anemia Macroangiopathic hemolytic anemia		(2 Hours & 51 minutes)
	Hematology & Oncology 5	Anemia of chronic disease Aplastic anemia Pure red cell aplasia (PRCA) Hemoglobin electrophoresis Acute intermittent porphyria Porphyria cutanea tarda Acute lymphoblastic leukemia Acute myeloid leukemia		(3 Hours)
	Hematology & Oncology 6	Chronic lymphocytic leukemia/Small lymphocytic lymphoma Hairy cell leukemia Chronic myeloid leukemia Polycythemia Vera Essential thrombocythemia Myelofibrosis Follicular lymphoma Mantle cell lymphoma Marginal zone lymphoma Burkitt lymphoma Diffuse large B-cell lymphoma Primary central nervous system lymphoma Adult T-cell leukemia/lymphoma Mycosis fungoides Hodgkin lymphoma		(3 Hours & 43 minutes)
	Hematology & Oncology 7	Multiple myeloma Monoclonal gammopathy of undetermined significance (MGUS) Waldenstorm macroglobulinemia Langerhans cell histiocytosis Hemophagocytic lymphohistiocytosis Chronic venous insufficiency (CVI)		(2 Hours & 22 minutes)
	Hematology & Oncology 8	Warfarin Heparin Low-molecular-weight heparins Direct thrombin inhibitors Direct factor Xa inhibitors Thrombolytics ADP receptor inhibitors Glycoprotein IIb/IIIa inhibitors Cilostazol, dipyridamole		(2 Hours & 49 minutes)
	Hematology & Oncology 9	Methotrexate 5-fluorouracil Azathioprine, 6-mercaptopurine Cladribine Cytarabine (arabinofuranosyl cytidine) Busulfan Cyclophosphamide, ifosfamide Nitrosoureas (Carmustine, lomustine, semustine, streptozocin) Bleomycin Dactinomycin (actinomycin D) Doxorubicin, daunorubicin Vincristine, vinblastine Paclitaxel, other taxols Cisplatin, carboplatin Etoposide, teniposide Irinotecan, topotecan Hydroxyurea BeVacizumab Erlotinib Cetuximab, Panitumumab Imatinib, Dasatinib Rituximab Vemurafenib, Dabrafenib		(2 Hours & 2 minutes)
Gastrointestinal System			10	28 Hours
	Gastrointestinal System 1	Primitive Gut Tube Development and Rotation of Midgut Ventral wall defects Gastroschisis Omphalocele Congenital umbilical hernia Tracheoesophageal Anomalies Hypertrophic pyloric stenosis Intestinal atresia "apple-peel" atresia Pancreas divisum Annular pancreas Imperforate anus		(2 Hours & 41 minutes)
	Gastrointestinal System 2	Vitelline duct Meckel's diverticulum Hirschsprung disease Peritoneum Retroperitoneal structures Important gastrointestinal ligaments Abdominal aorta and branches Superior mesenteric artery syndrome Nutcracker syndrome		(2 Hours & 55 minutes)
	Gastrointestinal System 3	Celiac trunk Portosystemic anastomoses Pectinate (dentate) line Digestive tract anatomy & Histology Liver tissue architecture Biliary structures		3 Hours & 12 minutes
	Gastrointestinal System 4	Femoral region Inguinal canal Diaphragmatic hernia Hiatal Hernia Indirect inguinal hernia Direct inguinal hernia Femoral hernia Radiology of the abdomen		3 Hours & 4 minutes
	Gastrointestinal System 5	Sialolithiasis Sialadenitis Salivary gland tumors Esophageal Rings and Webs Zenker diverticulum Mallory-Weiss syndrome Achalasia Gastroesophageal reflux disease (GERD) Barret Esophagus Diffuse esophageal spasm Infectious esophagitis Eosinophilic Esophagitis Sclerodermal esophageal dysmotility Esophageal Carcinoma		2 Hours & 48 minutes
	Gastrointestinal System 6	Gastrointestinal regulatory substances Acute gastritis Chronic gastritis Peptic ulcer disease Ménétrier disease Gastric carcinoma		(3 Hours)
	Gastrointestinal System 7	Carbohydrate absorption Vitamin/mineral absorption Peyer patches Lactose intolerance Celiac disease Tropical sprue Whipple disease Pancreatic insufficiency		(1 Hour & 57 minutes)
	Gastrointestinal System 8	Crohn’s disease Ulcerative colitis Toxic megacolon Irritable bowel syndrome Volvulus Intussusception Intestinal Adhesion Paralytic (adynamic) ileus Meconium ileus Necrotizing enterocolitis Acute appendicitis Carcinoid tumor		(3 Hours & 10 minutes)
	Gastrointestinal System 9	Acute mesenteric ischemia Chronic mesenteric ischemia Colonic ischemia Angiodysplasia Colonic diverticula Colonic polyps Adenoma to carcinoma sequence Familial adenomatous polyposis Gardner syndrome Turcot syndrome Peutz-Jeghers syndrome Juvenile polyposis syndrome Lynch syndrome Colorectal carcinoma		(2 Hours & 33 minutes)
	Gastrointestinal System 10	Pancreatic secretions Acute pancreatitis Chronic pancreatitis Pancreatic carcinoma		(1 Hour & 51 minutes)
	Gastrointestinal System 11	Bile Liver cirrhosis Serum markers of liver pathology Hepatic encephalopathy Spontaneous bacterial peritonitis Budd-Chiari syndrome Portal vein thrombosis Reye syndrome Hepatic steatosis Alcoholic hepatitis Alcoholic cirrhosis Nonalcoholic fatty liver disease Hemochromatosis Wilson disease Alpha-1 antitrypsin (A1AT) deficiency Hepatocellular carcinoma Metastasis to liver Hepatic adenoma Cavernous hemangioma Angiosarcoma		(2 Hours & 20 minutes)
	Gastrointestinal System 12	Jaundice Gilbert syndrome Crigler-Najjar syndrome Dubin-Johnson syndrome Rotor syndrome Physiologic neonatal jaundice Biliary atresia Cholelithiasis (Gallstones) Biliary colic Acute calculous cholecystitis Acute acalculous cholecystitis Gallstone ileus Porcelain gallbladder Ascending cholangitis Primary sclerosing cholangitis Primary biliary cholangitis Secondary biliary cholangitis Anal fissure		(3 Hours & 6 minutes)
	Gastrointestinal System 13	Histamine H2 blockers Proton pump inhibitors Antacid use Bismuth, sucralfate Misoprostol Octreotide Ondansetron Metoclopramide Aprepitant Laxatives Loperamide Sulfasalazine Orlistat Ursodiol (ursodeoxycholic acid)		(2 Hours & 12 minutes)
Behavioral Science			12	27 Hours
	Behavioral Science 1	Epidemiologic measures Incidence and Prevalence Crude, Specific, and Standardized Rates Interpreting Diagnostic and Screening Tests Pre-test Probabilities Post-test Probabilities The relationship between the screening test probability Selecting Screening Test Cutoff Values Receiver Operating Characteristic (ROC) Curve		(2 Hours & 50 minutes)
	Behavioral Science 2	Cross-sectional study Case-Control Study Cohort Study Twin concordance study Adoption study Relative Risk (Relative Risk Ratio) (RR) Attributable Risk (AR) Attributable Risk Percent (AR%) Absolute risk reduction Relative risk reduction Number Needed to Treat (NNT) Number needed to harm (NNH) Odds Ratio Experimental Studies (Clinical Trials, Intervention Studies) Features of Randomized Controlled Clinical Trials		(2 Hours & 24 minutes)
	Behavioral Science 3	Precision Accuracy Bias and study errors Answering Probability Questions Mean Median Mode Standard Deviation		(2 Hours & 26 minutes)
	Behavioral Science 4	Confidence Intervals (CI) P-Values and Hypothesis Testing Outcomes of statistical hypothesis testing Statistical Power (1- β) Statistical Significance vs. Clinical Significance Choosing the Right Statistical Test Pearson Correlation coefficient		(1 Hour & 25 minutes)
	Behavioral Science 5	Classical Conditioning Operant or Instrumental Conditioning Types of reinforcers Modeling, Observational, or Social Learning Therapy/Modification Based on Classical Conditioning Therapy/Modification Based on Operant Conditioning Immature Defense Mechanisms Mature Defense Mechanisms Transference and countertransference		(2 Hours & 21 minutes)
	Behavioral Science 6	Child Abuse Child neglect Vulnerable child syndrome Domestic Violence Elder Abuse Shaken baby syndrome Human sexuality Gender dysphoria Paraphilic disorders Sexual dysfunction Sexuality and aging Suicide Sleep architecture Narcolepsy Insomnia Sleep terror disorder Somnambulism (Sleep-walking) Neurotransmitters Associated with Sleep “SANDman”		(2 Hours & 27 minutes)
	Behavioral Science 7	Intelligence Quotient (IQ) Intellectual Disability Specific learning disorder Autism spectrum disorder Rett syndrome Conduct disorder Oppositional defiant disorder Separation anxiety disorder Tourette syndrome Attention-deficit hyperactivity disorder Delusions Disorganized thought Hallucinations Schizophrenia		(1 Hour & 54 minutes)
	Behavioral Science 8	Major depressive disorder Major depressive disorder with psychotic features Persistent Depressive Disorder (dysthymia) Depression with Seasonal Pattern (seasonal affective disorder) Depression with atypical features Manic episode Hypomanic episode Bipolar disorder (manic depression) Cyclothymic disorder Electroconvulsive therapy Maternal (postpartum) “blues” MDD with peripartum onset Postpartum psychosis Grief Generalized anxiety disorder Adjustment disorder Phobias Obsessive-compulsive disorder Body dysmorphic disorder Panic disorder Post-traumatic stress disorder Acute stress disorder Trichotillomania Selective mutism Hoarding disorder		(2 Hours & 26 minutes)
	Behavioral Science 9	Somatic symptom disorder Conversion disorder (functional neurologic symptom disorder) Illness anxiety disorder (hypochondriasis) Pseudocyesis Factitious disorders Malingering Depersonalization/derealization disorder Dissociative amnesia Dissociative identity disorder Anorexia nervosa Bulimia nervosa Binge eating disorder Pica Amnesias Delirium Dementia Personality disorders		(2 Hours)
	Behavioral Science 10	Substance use disorder Typical Antipsychotics (first-generation antipsychotics) Atypical antipsychotics (second-generation antipsychotics) Selective serotonin reuptake inhibitors (SSRIs) Serotonin-norepinephrine reuptake inhibitors (SNRIs) Serotonin syndrome Tricyclic antidepressants (TCAs) Monoamine oxidase inhibitors (MOAIs) Bupropion Mirtazapine Trazodone Varenicline Lithium		(3 Hours & 25 minutes)
	Behavioral Science 11	Physician-Patient Relationship Types of Questions and Statements Legal issues related to medical practice		(2 Hours & 47 minutes)
	Behavioral Science 12	Early development milestones Stranger anxiety Separation anxiety Disease prevention Major medical insurance plans Healthcare payment models Medicare and Medicaid Hospice care Quality and safety Quality measurements Swiss cheese model Types of medical errors Medical error analysis		(2 Hours & 39 minutes)